|
1-
|
Antibiotics are typically produced in fed batch reactors because
|
|
|
A -
|
antibiotic yields are generally higher when cells enter the stationary phase
|
|
|
B -
|
the precursors are often toxic to the cells
|
|
|
C -
|
antibiotic yields are generally higher when cell growth slows
|
|
|
D -
|
All of the above
|
|
2-
|
Inoculum preparation for the fermentation medium for penicillin takes place on
|
|
|
A -
|
wheat seeds
|
|
|
B -
|
barley seeds
|
|
|
C -
|
rice seeds
|
|
|
D -
|
All of these
|
|
3-
|
Which of the following event occurs during second phase of growth of P. chrysogenum?
|
|
|
A -
|
Synthesis of penicillin is high
|
|
|
B -
|
Mycelial mass increases
|
|
|
C -
|
pH increase
|
|
|
D -
|
Both (a) and (b)
|
|
4-
|
Which of the following changes occur during first phase of growth of Penicillium chrysogenum?
|
|
|
A -
|
Growth of mycelia occurs
|
|
|
B -
|
Ammonia is liberated in the medium
|
|
|
C -
|
Lactic acid present in the corn steep liquor is utilized at the maximum rate
|
|
|
D -
|
All of the above
|
|
5-
|
High yield of chlorotetracyclin requires
|
|
|
A -
|
no aeration
|
|
|
B -
|
continuous aeration
|
|
|
C -
|
aeration which does not affect the yield
|
|
|
D -
|
controlled aeration
|
|
6-
|
Streptomycin is produced by
|
|
|
A -
|
S. griseus
|
|
|
B -
|
S. griseoflavus
|
|
|
C -
|
S. aerofaciens
|
|
|
D -
|
S. ramosus
|
|
7-
|
Which of the following organism(s) produce(s) tetracycline?
|
|
|
A -
|
Steptomyces aureofaciens
|
|
|
B -
|
Steptomyces ramosus
|
|
|
C -
|
Nocardia sulphurea
|
|
|
D -
|
All of these
|
|
8-
|
Media used for the production of chlorotetracyclin consists of
|
|
|
A -
|
sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4Cl
|
|
|
B -
|
corn steep liquor, CaCO3 and (NH4)2SO4
|
|
|
C -
|
sugar, CaCO3 and (NH4)2SO4
|
|
|
D -
|
corn steep liquor, CaCO3, (NH4)2SO4 and NH4Cl
|
|
9-
|
Which of the following precursor is added in the medium to get penicillin G?
|
|
|
A -
|
Phenyl carbamic acid
|
|
|
B -
|
Phenyl acetic acid
|
|
|
C -
|
Ammonium sulphate
|
|
|
D -
|
Ammonium chloride
|
|
10-
|
Media composition for the production of streptomycin is
|
|
|
A -
|
soybean meal, glucose, peptone, malt extract, sodium chloride
|
|
|
B -
|
soybean meal, glucose, peptone, malt extract, ammonium chloride
|
|
|
C -
|
soybean meal, glucose, peptone, malt extract, calcium carbonate
|
|
|
D -
|
soybean meal, glucose, peptone, malt extract, ammonium sulphate
|
